Destroy All Humans! 2: Reprobed - Second Coming Edition is an open-world action-adventure game that revitalizes the classic 2006 title, enhancing gameplay and graphics for a modern audience. Players control Crypto, an alien tasked with navigating various global environments, including England, Russia, and the United States. The game features an engaging storyline where players complete missions and confront human foes, utilizing an array of weapons and abilities, such as mind control and advanced alien technology to achieve their objectives.

The Second Coming Edition offers a wealth of exclusive content, enriching the gaming experience. Included are collectible items like a 70cm Crypto statue and an Arkwobbler statue, alongside a beautifully embossed metal plate and an artbook. Additionally, the edition features an orchestral score on CD and digital downloads for the Reprobed: Challenge Accepted DLC, a Reprobed: Skin Pack, and the Destroy All Humans! – Clone Carnage, making it a comprehensive package for fans of the franchise.