Destroy All Humans! 2: Reprobed - Second Coming Edition revitalizes the classic 2006 game with modern graphics and gameplay mechanics. As players control Crypto, they traverse a variety of global locations, including England, Russia, and the United States, engaging in missions that pit them against human foes. The game emphasizes a blend of action and strategy, allowing players to wield an array of alien weapons and abilities, such as mind control and advanced technology to defeat their enemies.

This edition offers a rich package of additional content, featuring a 70cm Crypto statue, an Arkwobbler statue, an embossed metal plate, and an artbook. Players will also receive the orchestral score on CD, along with digital DLCs including 'Reprobed: Challenge Accepted' and 'Reprobed: Skin Pack'. The inclusion of 'Destroy All Humans! – Clone Carnage' further enhances the experience, making it a comprehensive offering for fans of the franchise.