Destroy All Humans! 2: Reprobed is an open-world action-adventure video game, a remake of the 2006 original, and the sequel to the remade Destroy All Humans! This game, developed by Black Forest Games, is the sixth installment in the franchise. Players assume the role of Crypto, exploring global locations like England, Russia, and the United States. The main goal is to complete missions and conquer human adversaries.

With a variety of weapons and abilities at their disposal, players can strategically defeat enemies by mind-controlling humans and utilizing advanced alien technology. Destroy All Humans! 2: Reprobed offers an engaging gameplay experience with diverse challenges and opportunities for creative combat tactics.