Prototype 2 is a third-person science-fiction adventure shooter game with an open-world environment. It is the sequel to the original Prototype game and was developed by Radical Entertainment and published by Activision. The game was initially released on PS3 and Xbox 360 in April 2012, followed by a PC release in JulyLater in August 2015, it was released on next-generation consoles like PS4 and Xbox One.

The game is set in New York Zero, a city ravaged by an epidemic, and it is divided into zones. The player takes on the role of Sergeant James Heller, who returns from the Middle East to find that his family has been killed by the epidemic. James is out for revenge, and his mission is to find the person responsible for his family's death.