Otoko Cross: Pretty Boys Dropout! is a block puzzler game developed by EastAsiaSoft for Windows. The game features 45 stages of block-sliding puzzles and a cast of 9 crossdressing "otokonoko" characters, each with their own backstories and outfits to unlock. The goal of the game is to slide blocks left and right to match groups of a single color and clear them to drop character icons towards exits at the bottom of the screen. Some exits need to be unlocked before they can be used, and new block mechanics will be introduced as difficulty ramps up.

The game also has a challenge mode and a dressing room mode where you can use the points earned to unlock outfits and backdrops in any order you like, and then assemble them into your own custom dioramas. Additionally, Naked Mode can be unlocked by finishing the main game, adding practically infinite replay value and fanservice to keep you coming back for more quality time with the boys!