Isle of Arrows is a game that blends the concepts of tower defense and roguelike games. It is a unique blend of the two genres that gives the player the unique experience of building defenses on an ever-growing land piece.

The player can choose from one of three available map pieces, each of which has its own randomly generated terrain and enemies. The map is split into multiple lanes, which the player can use to expand the land. The player can also choose to construct various types of defenses, such as archery towers, flag posts, etc. These towers can be placed in any of the three available slots on the map, and each tower has its own attack and defense value.

The game begins with the player getting a random number of coins. These coins can be used to construct and upgrade the towers and collect the various items and cards. Each run is unique, so the player will get a different number of coins, enemies, items, and cards.