World of Van Helsing: Deathtrap combines tower defense mechanics with action-RPG elements, immersing players in a gothic-noir world filled with horrors. Players must defend the Silent Forts from invading monsters by strategically placing traps and utilizing powerful spells. The game features a single-player campaign where players can tackle waves of enemies alone, as well as a cooperative mode that allows for teamwork on specially designed maps. Players can also engage in a competitive mode, where they take on the roles of defenders and attackers, adding a unique twist to the gameplay.

The game offers a wealth of content, including three distinct hero classes—Mercenary, Sorceress, and Marksman—each with unique skills and tactics. With 100 levels to achieve and over 50 skills per class, character development is extensive. Players can also customize their inventory with a detailed loot system and a variety of traps and upgrades. The game includes hidden areas for exploration, artifact crafting, and a leaderboard system for competitive play, ensuring that players have a rich and engaging experience.