True Crime: Streets of LA is a free-roaming action game available on Mac that immerses players in a vibrant, urban environment. Similar to Grand Theft Auto III, the game combines driving and action elements, allowing players to explore the city while engaging in various missions. The gameplay is structured around a series of missions that are primarily driven by the overarching narrative, enhanced by cutscenes that unfold the story.

Players can experience a non-linear progression through the game; even if a mission is failed, they can continue to play through the chapter and attempt later missions. This design choice introduces branching paths and optional missions, providing a dynamic gameplay experience. To complete a chapter, players must eventually succeed in all main missions, ensuring a comprehensive exploration of the storyline.