Sense: A Cyberpunk Ghost Story is a 2.5D role-playing game set in a dystopian 2083 Neo Hong-Kong. Players follow Mei-Lin Mak, a young woman with cybernetic enhancements, as she delves into a haunting mystery intertwined with her family's past. The game uniquely blends elements of traditional Chinese folklore with a futuristic backdrop, creating an immersive narrative experience. Players must navigate the eerie environment of the Chung Sing building while piecing together the stories of 14 lost souls, revealing the truth behind a family curse.

The game emphasizes atmosphere and storytelling over conventional horror tropes, opting for a slow build of tension rather than relying on jump scares. Mei-Lin's journey is marked by her vulnerabilities as a programmer rather than a fighter, making her confront the ghosts of her reality. This approach allows players to engage with the psychological aspects of horror, fostering an environment where the true fear emerges from within, challenging their perceptions at every turn.