Reina Valera Antigua 1569 (Biblia de la Reina Valera) is the most complete, with all the chapters of the Old and New Testaments. It was published in 1569, in a long-lasting partnership with the same printer as the previous one, but in a different location. It is the first Spanish translation of the Bible and the first book of the New Testament in Spanish, and it is the first one that was published in Spain.

The Reina Valera Antigua 1569 has a unique style, a beautiful and unique layout, with more than one hundred pages, and it has been designed to look as beautiful as possible. It is the most complete book in Spanish, with the most important books of the Old and New Testaments.