Plague Lords: Witch Hunt is a strategy game set in a medieval world plagued by a mysterious illness. Players command a small squad of mercenaries as they navigate through one of five main cities, battling infected foes and uncovering the secrets behind the epidemic. The game combines exploration with strategic combat, allowing players to engage in tactical battles while managing resources and building fortifications.

In addition to combat, players can construct and craft various items, including traps and barricades, to enhance their military camp. With a focus on strategy and resource management, Plague Lords offers a rich gameplay experience that encourages players to utilize their skills to survive in a dangerous environment. The blend of exploration, crafting, and combat mechanics creates a captivating narrative as players delve into the dark mysteries of the barony.