Niche: A Genetics Survival Game is an innovative blend of turn-based strategy and simulation that incorporates roguelike elements. Players create and evolve their own species of animal-like creatures, including cats, foxes, bears, and dogs, using real genetic principles. The game challenges players to ensure the survival of their species against various threats like predators, climate change, and diseases, emphasizing the importance of genetics in survival. If a species becomes extinct, players must restart their evolutionary journey.

The game features a dynamic world filled with procedurally generated environments and over 100 genes that influence the traits of the species. Players can explore five distinct biomes, each populated with unique predators, prey, and flora. The mechanics are inspired by population genetics theories, providing educational value by seamlessly integrating scientific concepts such as genetic drift and natural selection into the gameplay. Niche combines entertainment with learning, making it a unique experience for players.