MightyBox will save you loads of mouse movements and clicks, because it allows you to open apps and files just by pressin Ctrl+Spacebar on your keyboard and type in the name of the app or file you want to launch.

You can also choose the program with which to open files, browse the folder structure, open websites, move and copy files and even type in anything you like and save it as a text file. All these handy functions are presented under a nice interface that resembles that of QuickSilver, the popular Mac OS X app launcher.

Before starting to use MightyBox take a look at the basic documentation to make the most of it.