Misfortune Ramirez Hernandez is an 8-year-old with an imagination and a goal to find the prize of Eternal Happiness, to give to her mother. She is accompanied by her new friend, Mr. Voice, and together they venture into the woods, full of secrets and surprises.

Little Misfortune is a story-based game where the player's choices have consequences, set in the same world as the cult video game Fran Bow. It features a variety of activities, such as petting animals, visiting a pet cemetery, hearing Misfortune's voice, searching for missing children, encountering monsters, falling in love, and committing petty crimes.

The game features original artwork by Natalia Martinsson and an original soundtrack by Isak Martinsson.