"In the Darkness (ALPHA)" is a survival horror adventure quest. The story of the game is based on the idea that humans were able to find a way to prevent the destruction of the Earth by the sun. To do this, they developed a vaccine, which gave people the ability to resist the effects of the sun. However, the vaccine also caused a change in the behavior of the people who were given it. They became aggressive, attacking other people, and it was only with great difficulty that the people were kept in control.

The main characters of the game are Mike, the main character, and his friend, Brad. They are the only people who are not infected with the vaccine. They decide to go on a journey to find a way to cure the vaccine, and the story of the game is based on their journey.