Hitman 3: Patient Zero Requiem offers players an immersive strategy experience as Agent 47 embarks on a critical mission to eliminate Lilith Devereux, a rising figure in the corporate world. Set in the atmospheric Carlisle Estate in Dartmoor, players must navigate through a web of intrigue surrounding Devereux's rapid ascent, which is linked to the mysterious deaths of her predecessors. The game emphasizes strategic planning and execution, allowing players to choose their approach to completing the mission, whether through stealth or direct confrontation.

The game is designed for the PlayStation 4 and features a full version license, enhancing the overall gaming experience. Players will encounter various challenges as they explore the estate, interact with NPCs, and uncover secrets that could aid in their mission. The blend of strategy and action, along with a compelling narrative, makes Hitman 3: Patient Zero Requiem a noteworthy addition to the franchise.