You can play the game online or offline, with your friends or alone, at any time and anywhere.

If you want to play online, just log in using your Facebook account or email address, and you are ready to go.

You can also participate in the #GenigmaChallenge, where you can help the team to map the entire genome of the T47D cell line. You can also be part of the research, by sending your data to the team.

You can also create your own challenges. In this case, the pieces have to be placed in the right order to create a specific change.