Expeditions: Conquistador is a turn-based strategy RPG set in the 16th century, where players take on the role of Spanish explorers seeking fortune and glory in the New World. The game features a rich narrative divided into two campaigns, offering over 25 hours of engaging gameplay that challenges players through resource management and tactical combat. Players can create their expedition by choosing from over 30 unique characters, each with distinct traits and moral standards, which adds depth to the decision-making process.

The game emphasizes choice and consequence, allowing players to forge alliances with indigenous tribes or engage in fierce battles against them. With four customizable difficulty levels, including the challenging Iron Man mode, Expeditions: Conquistador caters to both seasoned strategy veterans and newcomers. Players can also engage in PvP combat via Hot Seat mode or TCP/IP, enhancing the game's replayability and competitive edge.