Doki Doki Daigaku: Anime Idol Girlfriend Romance is a Japanese otome game. The story is set in the summer of 2019, at a girls' university in Japan. The characters are the students of WISH, a band that has just signed a record deal with a major label. The game is about WISH's romance, friendship, and struggles.

The game starts with the members of WISH, Kiko, Sae, Jun, and Rolo, having a free summer. They decide to attend the summer school at the university. They are not the only ones at the school; there is also a rival school, which has its own students and faculty. The students of the rival school are known as the Straw Hat girls, because they wear straw hats. The girls at the university have their own problems and issues. The story is about how the members of WISH solve their problems and issues, and how they become the best girls in the world.