The Case-book of Sherlock Holmes is a collection of detective stories about Sherlock Holmes. Each story is told by a different author and is based on a different plot. The stories are not set in the same world and take place in different times and places. The main character is Sherlock Holmes, the world's best detective. His friend and companion is Dr. Watson, the best medical doctor in the world. They are often called upon to help solve cases that have a mystic and obscure solution.

In order to help solve the mysteries, Sherlock Holmes and Dr. Watson need to follow certain rules. They need to follow the rules of investigation and the most important is that they need to have the best knowledge and expertise in medicine and science.

If you have a scientific background, you can use your expertise to help solve the mysteries.