Cartoon Defense 5 is a new action game from MolaMola Inc. that comes back more powerfully than ever before. With an unexpected menace, the player must defeat renewed and various enemies to save the world. The game follows the story of our hero, who became the king of the Cartoon kingdom after defeating a big dragon, Kirimu. However, the peace is short-lived as one of the great old ones has been awoken and menaces the Cartoon world. The player must defeat the enemies before they become fully awake and ruin the world.

The game features a defense action gameplay that requires the player to kill surging enemies. The combat system is hotter than before, and the player can raise their hero with various costumes. The player can also make their own tower with various parts combinations and enjoy mini-games at their camp. Additionally, there is a more powerful upgrade system, and the game offers a new mid-boss every region.