Bacteriophage is an innovative roguelike platformer that immerses players in the unique environment of the human body, battling bacterial infections. Players take on the role of Terri, a cyborg armed with a gun that fires bacteriophage DNA-infused bullets. The game's objective is to navigate through various bodily systems, confronting and eliminating harmful bacteria and infections encountered along the way. The gameplay combines classic platforming mechanics with strategic elements typical of roguelikes, allowing for a fresh experience with each run.

The design of Bacteriophage emphasizes a vibrant and engaging aesthetic that reflects its biological theme. Players can expect a variety of challenges as they progress through levels, each filled with different types of bacteria and obstacles. The full version offers a complete gaming experience, showcasing the blend of action and exploration while also educating players about the microscopic battles occurring within the body.