Alien Rampage is a 2D side-scrolling action game that immerses players in a vibrant and chaotic alien world. Released in 1996, the game features large animated sprites and intricate parallaxing backgrounds that enhance the visual experience. Players assume the role of a lone alien, navigating a hostile environment after crash-landing on an inhospitable planet. The primary objective is to reach a spaceship while combating numerous enemies, including hostile creatures and bounty hunters, utilizing an array of powerful weapons.

The gameplay is centered on fast-paced running, jumping, and shooting mechanics, with a significant focus on the shooting aspect. The game is noted for its gory action, drawing comparisons to classic titles like DOOM, but in a 2D format. Players can also engage with local troll-like natives for assistance and power-ups, adding a layer of strategy to the chaotic combat.